Home Mitochondrial & Cellular Research MOTS-c
Vial of MOTS-c research compound with silver cap and Suria label, lit against a dark background with warm gold ambient light

Overview

A mitochondrial-derived signaling peptide.

MOTS-c is a 16-amino acid peptide encoded within the mitochondrial genome itself, rather than nuclear DNA — a distinguishing feature among mitochondrial-derived peptides. It is studied for its role in activating AMPK, a central regulator of cellular energy balance, and for its involvement in the folate-methionine cycle.

Suria's MOTS-c is synthesized to high purity and independently verified prior to release, giving researchers a consistent starting point for metabolic signaling and exercise-physiology research models.

Research Use Only. Not for human or veterinary use.

Specifications

Documented, down to the molecule.

Purity
≥98% (HPLC)
Sequence
Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg (16 amino acids)
Molecular Formula
C101H152N28O22S2
Molecular Weight
2,174.6 g/mol
CAS Number
1627580-64-6
Storage
−20°C, lyophilized; protect from light and moisture
Appearance
White to off-white lyophilized powder
Research Category
Mitochondrial & Cellular Research

Third-Party Testing

Independently verified.

Analytical documentation, when available.

Available third-party analytical documentation for MOTS-c can be reviewed for applicable batches through Suria's Batch Documentation system. We believe documentation should be held to the same standard as the research it supports.

Certificates of Analysis will be available at time of launch.

Research Highlights

Why researchers study it.

Metabolic Signaling

Studied for its activation of AMPK, a key regulator of cellular energy homeostasis.

Exercise Physiology

Frequently examined in research models of exercise capacity and metabolic adaptation.

Mitochondrial Origin

Unusual among bioactive peptides for being encoded directly within mitochondrial DNA.

Emerging Research

An active and growing area of literature since its identification in 2015.

Storage

Handled the way research deserves.

Lyophilized vials

Store as specified above, protected from light and moisture, until ready for reconstitution.

Reconstituted solution

Store at 2–8°C and use within the recommended window for your protocol.

Handling

Avoid repeated freeze-thaw cycles to help preserve peptide integrity across a research protocol.

Research Use Only. Not for human consumption.

Frequently Asked Questions

Good to know before you order.

How is it shipped?
Orders are packaged with care and shipped using protective, secure methods designed to help each vial arrive in excellent condition.
How should it be stored?
Store lyophilized vials as specified above, away from light and moisture. Once reconstituted, store at 2–8°C and use within your protocol's recommended window.
Is this for human consumption?
No. MOTS-c is sold strictly for laboratory and scientific research use. It is not intended for human or veterinary use, and is not a drug, dietary supplement, or food.
Why does purity matter?
Purity directly affects the reliability of research outcomes. Available third-party analytical documentation can be reviewed for applicable batches through Suria's Batch Documentation system.

Batch Documentation

View available analytical documentation for this research product.

View Documentation